Saturday, April 26, 2014

ANTI-LINGO? NEW ANGLE BIIB033 Myelin Repair


My neurologist has been talking to me about this new treatment in clinical studies right now.
We're talking myelin repair here!!

Here's the link to the Fact Sheet from Biogen Idec  
http://www.biogenidec.com/Files/Filer/VPR/press_materials/aan2013_EN/FactSheet-Anti-LINGO-1-FINAL-7Mar13.pdf

Key point...CLINICAL STUDIES 
Biogen Idec has completed two placebo-controlled Phase 1 studies with anti-LINGO-1. These 
studies included both healthy volunteers and subjects with MS. 
Key findings from the Phase I studies:4


- Following a single IV dose in healthy volunteers and two repeated IV doses in MS subjects, 
anti-LINGO-1 appeared to be safe and well tolerated. 
- Anti-LINGO-1 pharmacokinetics in serum and CSF appeared to be similar between healthy 
subjects and MS subjects. 
These findings supported advancing anti-LINGO-1 monoclonal antibody into the Phase 2 clinical 
study that is underway

Such exciting news...we should know in a year, maybe 2, if this will be successful.  I'll keep you posted...
or check out BIIB033 on "clinicaltrials.gov"


No comments: